22 MPG combined isn’t going to win any awards in the mid-size luxury sedan segment, but it’s a figure most 2020 Lexus GS 350 F Sport buyers have already factored into their ownership experience. This isn’t a hyper-efficient hybrid designed to sip fuel; it’s a traditionally-engineered, naturally-aspirated sport sedan with a smooth, powerful V6 delivering a refined driving experience. These priorities often come at a price, and in this case, that price is at the pump.

City and highway performance

The EPA estimates the GS 350 F Sport at 19 MPG in the city and 27 MPG on the highway. The city figure reflects the reality of stop-and-go traffic, where the 3.5L V6 works harder and the eight-speed automatic cycles through gears more frequently. The highway MPG demonstrates the engine’s ability to cruise efficiently at steady speeds. Owners find these estimates to be reasonably accurate, dependent on driving style and traffic conditions. Aggressive acceleration and frequent braking in urban environments will undoubtedly push the city MPG lower, while long highway stretches at consistent speeds should deliver figures closer to, or even slightly above, the EPA estimate.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2020 Lexus GS 350 F Sport at $2,650. This calculation is based on driving 15,000 miles per year and using national average fuel prices. Individual fuel costs will vary depending on driving habits, local fuel prices, and the type of fuel used. While the GS 350 F Sport doesn’t require premium fuel, some drivers prefer it for potentially improved performance, adding to the annual expense. The $2,650 is an average; your own costs could be significantly higher or lower.

Real-world expectations

Do GS 350 F Sport drivers actually achieve 22 MPG combined? The answer depends. Those who prioritize the F Sport’s performance and enjoy its lively throttle response will likely see numbers slightly below the EPA estimate. Drivers who adopt a more conservative driving style, anticipate traffic, and use the car’s drive modes carefully can get closer to the advertised figures. Factors like tire pressure, vehicle maintenance, and even aerodynamics (avoiding roof racks, for example) also play a role. Most owners accept that fuel economy isn’t the GS 350 F Sport’s strongest suit, but they appreciate the trade-off for the driving experience it provides.

How it compares

Compared to its competitors, the GS 350 F Sport’s fuel economy sits in the middle of the pack. The BMW 540i xDrive, with its turbocharged inline-six, achieves a slightly better 25 MPG combined. The Mercedes-Benz E450 4Matic also gets 25 MPG combined. These German rivals have used turbocharging and advanced engine management to achieve better fuel efficiency without sacrificing performance. The Acura TLX SH-AWD with the V6 manages only 23 MPG combined, showing that displacement alone doesn’t dictate fuel consumption. Buyers considering the GS 350 F Sport often prioritize Lexus’ reputation for reliability and build quality over outright fuel efficiency, accepting the slightly lower MPG as a trade-off. You can see GS MPG across all years on our site to explore older models.

Tips to maximize efficiency

Aggressive acceleration leads to poor fuel economy. The GS 350 F Sport encourages spirited driving, but resist the urge to floor the accelerator at every opportunity. Gentle acceleration allows the engine to operate more efficiently, especially from a standstill. This is particularly relevant in city driving, where frequent starts and stops can significantly impact fuel consumption.

Use the GS 350 F Sport’s drive modes. The “Eco” mode adjusts throttle response and transmission settings to prioritize fuel efficiency. While it might slightly reduce the car’s sporty character, it can make a noticeable difference in MPG, especially during longer highway drives or in stop-and-go traffic. Experiment with different modes to find the best balance between performance and economy for your driving needs. If you’re concerned about fuel economy from the very beginning, you can also find all Lexus fuel economy data here.

Maintain proper tire inflation. Underinflated tires increase rolling resistance, forcing the engine to work harder and reducing fuel efficiency. Check your tire pressure regularly and inflate them to the recommended level, which can be found on a sticker inside the driver’s side doorjamb. A simple tire gauge can save you money at the pump and improve handling.

Avoid unnecessary idling. Letting the engine idle for extended periods consumes fuel without covering any distance. If you’re stopped for more than a minute or two, turn off the engine. Modern cars start quickly and easily, and the fuel saved by avoiding idling can add up over time. This is even more important in urban environments with frequent traffic lights and congestion.